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single-cell high-throughput microfluidic tapestri platform  (Mission Bio)

 
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    Structured Review

    Mission Bio single-cell high-throughput microfluidic tapestri platform
    Clonal architecture of TP53 -mutated MPN patients. Phylogenetic trees show the order of mutation acquisition during MPN history with maximum likelihood in 8 patients. The mutational history was manually reconstructed from the single-cell data. In the case of MPN3, it was not possible to infer the order of mutation acquisition in JAK2 and U2AF1 because of the absence of cells with wild-type version of these genes. Each circle represents a clone identified in single-cell analysis using <t>Tapestri</t> platform and Tapestry Insights software (Mission Bio). The size of each circle denotes the relative clone size. The nomenclature of each mutation is indicated only when 2 or more mutations were present in the same gene.
    Single Cell High Throughput Microfluidic Tapestri Platform, supplied by Mission Bio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/single-cell+high-throughput+microfluidic+tapestri+platform/single+cell+high+throughput+microfluidic+tapestri+platform/pmc09092407-105-6-18
    Average 90 stars, based on 1 article reviews
    single-cell high-throughput microfluidic tapestri platform - by Bioz Stars, 2026-11
    90/100 stars

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    1) Product Images from "Single-cell analysis reveals selection of TP53 -mutated clones after MDM2 inhibition"

    Article Title: Single-cell analysis reveals selection of TP53 -mutated clones after MDM2 inhibition

    Journal: Blood Advances

    doi: 10.1182/bloodadvances.2021005867

    Clonal architecture of TP53 -mutated MPN patients. Phylogenetic trees show the order of mutation acquisition during MPN history with maximum likelihood in 8 patients. The mutational history was manually reconstructed from the single-cell data. In the case of MPN3, it was not possible to infer the order of mutation acquisition in JAK2 and U2AF1 because of the absence of cells with wild-type version of these genes. Each circle represents a clone identified in single-cell analysis using Tapestri platform and Tapestry Insights software (Mission Bio). The size of each circle denotes the relative clone size. The nomenclature of each mutation is indicated only when 2 or more mutations were present in the same gene.
    Figure Legend Snippet: Clonal architecture of TP53 -mutated MPN patients. Phylogenetic trees show the order of mutation acquisition during MPN history with maximum likelihood in 8 patients. The mutational history was manually reconstructed from the single-cell data. In the case of MPN3, it was not possible to infer the order of mutation acquisition in JAK2 and U2AF1 because of the absence of cells with wild-type version of these genes. Each circle represents a clone identified in single-cell analysis using Tapestri platform and Tapestry Insights software (Mission Bio). The size of each circle denotes the relative clone size. The nomenclature of each mutation is indicated only when 2 or more mutations were present in the same gene.

    Techniques Used: Mutagenesis, Single-cell Analysis, Software

    Related Articles

    Software:

    Article Title: Single-cell analysis reveals selection of TP53 -mutated clones after MDM2 inhibition
    Article Snippet: Clonal architecture was determined using the single-cell high-throughput microfluidic Tapestri platform coupled to the Tapestri Insights bioinformatics software (Mission Bio).

    Mutagenesis:

    Article Title: Single-cell analysis reveals selection of TP53 -mutated clones after MDM2 inhibition
    Article Snippet: Clonal architecture was determined using the single-cell high-throughput microfluidic Tapestri platform coupled to the Tapestri Insights bioinformatics software (Mission Bio).

    Single-cell Analysis:

    Article Title: Single-cell analysis reveals selection of TP53 -mutated clones after MDM2 inhibition
    Article Snippet: Clonal architecture was determined using the single-cell high-throughput microfluidic Tapestri platform coupled to the Tapestri Insights bioinformatics software (Mission Bio).



    Similar Products

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    Mission Bio single-cell high-throughput microfluidic tapestri platform
    Clonal architecture of TP53 -mutated MPN patients. Phylogenetic trees show the order of mutation acquisition during MPN history with maximum likelihood in 8 patients. The mutational history was manually reconstructed from the single-cell data. In the case of MPN3, it was not possible to infer the order of mutation acquisition in JAK2 and U2AF1 because of the absence of cells with wild-type version of these genes. Each circle represents a clone identified in single-cell analysis using <t>Tapestri</t> platform and Tapestry Insights software (Mission Bio). The size of each circle denotes the relative clone size. The nomenclature of each mutation is indicated only when 2 or more mutations were present in the same gene.
    Single Cell High Throughput Microfluidic Tapestri Platform, supplied by Mission Bio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/single-cell+high-throughput+microfluidic+tapestri+platform/single+cell+high+throughput+microfluidic+tapestri+platform/pmc09092407-105-6-18
    Average 90 stars, based on 1 article reviews
    single-cell high-throughput microfluidic tapestri platform - by Bioz Stars, 2026-11
    90/100 stars
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    Clonal architecture of TP53 -mutated MPN patients. Phylogenetic trees show the order of mutation acquisition during MPN history with maximum likelihood in 8 patients. The mutational history was manually reconstructed from the single-cell data. In the case of MPN3, it was not possible to infer the order of mutation acquisition in JAK2 and U2AF1 because of the absence of cells with wild-type version of these genes. Each circle represents a clone identified in single-cell analysis using Tapestri platform and Tapestry Insights software (Mission Bio). The size of each circle denotes the relative clone size. The nomenclature of each mutation is indicated only when 2 or more mutations were present in the same gene.

    Journal: Blood Advances

    Article Title: Single-cell analysis reveals selection of TP53 -mutated clones after MDM2 inhibition

    doi: 10.1182/bloodadvances.2021005867

    Figure Lengend Snippet: Clonal architecture of TP53 -mutated MPN patients. Phylogenetic trees show the order of mutation acquisition during MPN history with maximum likelihood in 8 patients. The mutational history was manually reconstructed from the single-cell data. In the case of MPN3, it was not possible to infer the order of mutation acquisition in JAK2 and U2AF1 because of the absence of cells with wild-type version of these genes. Each circle represents a clone identified in single-cell analysis using Tapestri platform and Tapestry Insights software (Mission Bio). The size of each circle denotes the relative clone size. The nomenclature of each mutation is indicated only when 2 or more mutations were present in the same gene.

    Article Snippet: Clonal architecture was determined using the single-cell high-throughput microfluidic Tapestri platform coupled to the Tapestri Insights bioinformatics software (Mission Bio).

    Techniques: Mutagenesis, Single-cell Analysis, Software